Conférence « Functional circuits involved in motor learning »

Chères Collègues et Doctorantes
Chers Collègues et Doctorants

Le Prof. Agnès Gruart de l’Universidad Pablo de Olavide à Séville 
sera de passage à Bruxelles en novembre prochain.  
A cette occasion, elle tiendra une conférence intitulée 'Functional 
circuits involved in motor learning"

“Il n'y a pas d'action ou de traitement cognitif qui puisse être fait 
sans le cerveau”
L’Ecole Doctorale des Sciences de la Motricité du FNRS vous y invite 
toutes et tous, et dans l’attente de vous rencontrer nombreux à cette 
occasion, vous trouverez ci-dessous, un extrait de sa communication.

Contact pour plus d’informations : Prof Guy Chéron / Tél : 02/555 34 03

Cette conférence aura lieu sur le 19 novembre 2018 à 12h30 à l'ULB sur le Campus Erasme à la
Faculté des Sciences de la Motricité - Bâtiment N / Niveau 3 - Auditoire N.3.111
Extrait :
The complexity of brain functions can only be approached by a multidisciplinary and
comparative approach. The availability of genetically manipulated mammals (mice and
rats) and of sophisticated electrophysiological techniques, susceptible of being applied in
behaving animals during the acquisition of new motor abilities, have largely facilitated
his approach.

Our group has studied for years the contribution of sensory, motor, premotor, hippocampal, 
and prefrontal circuits to non-associative, pavlovian, and instrumental learning paradigms. 
For this, we have recorded activity dependent changes in strength in cortical and subcortical 
synapses during the respective acquisition process.

Recently we have concentrated our attention to the contribution of prefrontal circuits to
the acquisition and storage of instrumental learning tasks, including cooperative learning
and decision making in mice and rats.  The main hypothesis of our studies is that learning 
is the result of the activity of wide cortical and subcortical circuits activating functional
properties of involved synaptic nodes. In particular, unitary firing, synaptic and local field  
potentials recorded in prefrontal sites are modified during the acquisition of the abovementioned 

In addition,  I will present recent evidences on the available information from our laboratory 
with respect to the use of these functional states for brain-machine interphase in behaving rats 
and for  coordinated cooperation between pairs of rats aimed to achieve simultaneous rewards.